I did a 5 day section hike last summer with no resupplies using a frameless pack that weights 240g or about 8.5oz. Total weight was: 3.8kg base weight, 3.5kg food, max volume of water 2.2 liters/kg = 9.5kg or about 21lbs.
My back didn't hurt. My shoulders didn't hurt. Nothing hurt. Sure, I was a bit sore sometimes, but that's to be expected hiking 20-30km through rough terrain no matter what kind of backpack you use. But I generally felt great. At the end of the trip I felt wonderful and I wish I could have gone another week or even a month, though I did miss my family.
I am going on another 5 day section hike in May, again without resupply, and this time I plan on taking 3.3kg base weight, 3.3kg food, and max volume of water 1.8liters/kg, total 8.4kg or 18.5lbs. Same pack as last time.
If and when I do a thru-hike for over a month, I would still take a frameless pack. But rather than my Zpacks Zero I would take my MLD Exodus (more volume). Many people have done thru-hikes with frameless packs. Zpacks Joe is a triple crowner and did all three thru-hikes with a frameless pack.
But you seem like your mind is made up Max. I say just go out there and enjoy your 5lb pack :)
I am curious, however, what is your height, weight, and body type Max? This is a factor that is often overlooked in contributing to comfort while backpacking. I am about 6ft tall, 185lbs, somewhat athletic build.

