You will have to experiment for yourself, Haakon, but I like AD and Airmesh next to skin. As I mentioned in the same post that you clipped, Brynje does add a small benefit — it isn’t so much that AD compromises the mesh as AD is mesh itself, which is why it has some of the benefit of mesh without adding a dedicated mesh layer.
I don’t find durability to be an issue. Both Airmesh and AD will get slightly thinner with use, but that’s actually a good thing IMO. Both remain plenty strong and lofty enough to do the job. I do use two layers in cooler weather.
Regarding temperature control and moisture management, I agree with all of you, and will add that temperature makes a difference.
I can work pretty hard in freezing weather or somewhat below without approaching saturation of any layers. It’s a combination of factors: layers that move moisture outward, including a breathable wind shell, plus adjusting ventilation and layers to remain comfortably cool. I accumulate a little moisture in my layers at some points, but it will quickly cook away when I slow down. Half an hour after stopping I am completely dry.
I frequently use zippers and adjustments around head, neck, and wrists to adjust cooling. Yes, part of it is experience or skill or whatever you want to call it.
It’s more challenging in very cold weather when I am wearing more insulation that doesn’t breathe so well, especially when it is cold and windy enough that all skin must remain covered at all times. In those cases, it can be easier to adjust pace rather than fiddle with layering to maintain comfort and avoid saturating layers with sweat/condensation.
That doesn’t necessarily mean a slow pace — it means keeping the power output more or less consistent, including hills.