I don’t own either (I do own a cuben Solomid XL) and my thoughts are as follows:
The duomid negatives:
could be a little short for people over 6′ (peoples experiences tend to vary on this one)
TIGHT for two – the duplex would be better for two people
Kind of heavy when used with the inner all the time – though it is modular – I use mine sans bug inner when I can.
The duplex negitives:
not as wind worthy (but much more room for two)
sloppy looking pitch (at least the ones I have seen)
not modular
lighter weight cuben standard (though the 0.74 is available)
not as good of fit and finish as compared to MLD (but perfectly serviceable)
If I were using it for two people where I needed bug protection most of the time, I would go with the Duplex. If I were using it solo and wanted to be able to use the shelter with or without bug protection I would get the Duomid.
Bonus points in the Duomid’s favor if you camp often above treeline.
Deduct points from the Duomid if you are going to use it for two often (You might look at the Locus Gear Happi or HMG Ultamid 2 instead for two people.)