Jason, Both the Osprey Talon and Exos 46 are nice packs. I think it comes down to which one fits you best. For some reason the Exos just didn't fit well for me. After returning my Osprey Hornet, I actually wanted the Exos over the Talon, but fit came into play. FWIW here are the major items of gear that I have fit reasonably into the Talon 44, the ULA Ohm, and the SMD Swift:
Tent – TT The Moment
Sleeping Bag – WM Summerlight
Clothes Bag with raingear.
Homemade alcy stove and pot
Sleeping Pads – Z-rest or KookaBay Inflatable
First aid kit and toiletries
Bearikade Weekender bearcan.
2 32 oz. bottles – 1 on shoulder strap, 1 in side pocket.
Patagonia – Nano Puff to take up space around bear can.
Without the bear can ALL of the above packs would serve you well. With a bear can, I wasn't as impressed with the OHM or Swift. I have a Circuit on order and will let you know how it fares with a bear can if that is a requirement or not for you.
Keith, I love the photo of the wooden backpack! Inquiring minds want to know if you use it for real, or is it a great conversation starter!