Me, I just love my monster pack. It's somewhere between 85 and 95 litres and weighs over 6lb. Would I use it for a solo trip under a week? No way, but for my trip last week, it was great.
We went out with the family for eight days to the Walls of Jerusalem in Tasmania. Anyone who knows Tassie will know that there is the potential for snow anytime, even midsummer (which it is here) There's also the GUARANTEE of rain on at least some of those days. We had 250mm (Yep 10 inches) in one day on this trip.
Before we left my wife was unsure if she could walk with a pack at all, due to an inflamed TFL insertion. She tried a 25lb pack for 12km of flat walking, and was okay, but I didn't want to push her to carry any more. She also suffers from Reynards, so needs to pack extra dry/warm clothing. The kids (9 and 11) both had all their own gear, but no food, cooking gear or shelter.
This left me with a four person shelter (Old school BD Megamid, not Megalite, with nest against leeches and mossies), four person cooking setup, water treatment and diversions for tentbound days, plus a sat phone for emergency contact and pickup at the other end (The road ended up being washed away, but our friends were able to 4wd past this to meet us for pickup). I also carried a family first aid kit (Two of the snakes prevalent down there are deadly;Tiger and Brown, but the White Lipped will only make an adult really sick. We only saw a White Lipped.) I also had food for 28 person/days at about 1.75lb pppd. The two kids will consistently out eat many adults. (We walked out with 4 muesli bars, a bag of gorp, and three serves of dehy baked beans left over)
In all honesty, the only time I felt any discomfort from the PACK was on the last day when we packed up wet, and I was carrying some of the kids gear for eight km of offtrack walking, followed by eight km on a rocky 4WD track. My left shoulder was aching, but I'm not sure that wasn't from lifting something, since it continued to hurt at home. The pack carried great. Could I feel the weight on the first few days….absolutely. Knees and achilles copped a pounding, but I knew that before I started, and prepared adequately. By the end, 35lb was riding like a cloud. I never heard a single complaint from the kids or my wife about their loads.
My monster pack allowed us to take my dream trip, and turn it into a reality, and help show my kids and wife what they're capable of. My nine year old daughter is demanding a repeat trip in winter!

Middle of summer hiking in Tasmania!