Jim and Jim,
"It's always bugged me to have no objective comparison of the insulation value of an ounce of down vs an ounce of synthetics"… things are even worse in the realm of synthetics. All of the synthetic insulation garments I have tested provide less insulation than the insulation manufacture's clo/oz published specifications. Sometime in the future, I will talk about this in more detail. In the mean time I am leaving for a one month trip to tramp the bush.
The average commercial mummy sold in the US for three season use has a US advertised temperature rating of 20F. Ironically the EN13537 would only give this bag a Comfort rating of only 40F but that is another topic. It is an 800 fill mummy shaped and has a hood, draft tube, 40 denier fabric, circular neck collar with a draw cord and 3.25 inch baffles throughout the body. The same bag manufactured with different levels of overfill yield the following values.

“1) I just want to double check your 2.16kg/m^3 and 75kg/m^3 figures for typos. If I read correctly, the optimal clo/thickness ratio is achieved at almost 35 times that typically used in LW bags!?”
2) “As Jim mentioned above, for LW backpackers, clo/oz is often a more valuable metric than clo/in. What density optimizes clo/oz?”
1) Since geese like people are quite individual, the curves for each batch of 800 fill down tested will be different but the average is found in the following table. The curve looks like a hockey stick. The clo increase verses density is approximately linear from 2.16 kg/m^3 to 18 kg/m^3. It then changes its slope to become almost flat until ~ 75 kg/m^3 where the clo starts to decrease. As UL backpackers we are only concerned with the linear segment of the curve.

2) For all practical purposes the clo/kg for different density stuffed bags are equivalent. Granted there is a~3 % benefit for the lowest density but is in the realm of computational noise.