Using a pack made from 1-2 osy nylon would drive me nuts since it would be so floppy.
If the pack is sized appropriately for your gear and consumables and compresses well enough, then the thin nylon feels almost the same as wearing any other well-packed backpack (moderately stuffed full, but not stuffed so tightly to form a tight cylinder shape either). The only minor downside to thin nylon is that the pack does feel slippery on your back and undersides of the shoulder straps IMHO.
The obvious remedy to the slickness would be to use a heavier material for the bottom and back and for the underside of the shoulder straps. This would also allow for stronger seams to hold the shoulder straps to the backpack, hold daisy chain to the straps, and to hold any hip belt attached via the seam between the side panels and the lower back panel.