Since we catch 30 salmon and 6 halibut each year (plus berries and rhubarb) we do a lot fo vac-packing in a Food Saver.
For liquids (and berries), freeze them first, then vac-pack them. Otherwise, the liquid gets sucked up into the vac-packer, mucks it up, and ruins the seal.
You can hit the “manual seal” button without the vacuum, but that is no different than putting the liquid in a ziplock bag and freezing it for our purposes of long-term storage at home, but for trail use, it would give you the liquid in that sturdier, better-sealed plastic.
If I wanted a water-based liquid sealed in with no air, I’d freeze it in an unsealed vac-bag bag (so it froze into a bag-sized shape), then vac-pack and heat-seal it. Most oils will freeze solid in a freezer and you could do the same with them.
Two, unrelated vac-packing tricks:
Freeze berries on wax paper on a cookie sheet BEFORE vac-packing them. Then you end up with whole, intact berries months later instead of a glacier of frozen berry mush.
You can “glaze” frozen meats and fish with a mist of water several times to build up a layer of ice around the meat. While that is sort of belt-and-suspenders since the vacuum bag is supposed to provide that protection, it does help with long-term (several years) storage. It is also a way to use zip-lock bags, Saran wrap, or freezing paper in lieu of vac-packing bags.