I'm not sure about current packs – but here are some insights that may help you.
I think the granite gear vapor trail was the best pack I used on the AT. It had a 1/8" piece of flexible plastic sheet along the back as a frame.
This just made it easier to pack by holding itself open/upright — it didn't really transfer weight like a frame.
The reason the vapor trail worked so well was because the pack was S-curved to fit into your lower back, and it had a great hip belt and good shoulder straps.
The rear straps made a great place to put you foam "rest break" pad (which many AT hikers use several times a day).
The water bottle pockets were too high for me to reach.
The go lite jam was a pretty good runner up for me.
Again, the secret was the S-curved back, a good hip belt, and decent shoulder straps.
The jam's hip belt was a little floppy though, and this allowed the pack to bounce a little when walking.
The rear pocket was super convenient.
The water bottle pockets were low enough to remove and replace a water bottle when walking.
The REI flash (old version) was a good 3rd place pack.
This one had a medium stiff (removeable) plastic framesheet, and no wire in the hip belt.
The hip belt was better (less floppy) than the Jam, and the shoulder straps were about the same.
The stuff pocket was good for rain gear, snacks, etc – but not as easy to use or as high capacity as the Jams pocket.
The water bottle pockets on the 50liter were part of the stuff pocket – and didnt allow me to access water while walking.
The flash pack actually carried BETTER as a frameless pack.
I think this was because it could be squished into an S-curve shape, and then the lowe section of the pack could be sucked into the lower back with the hip belt, and everything else just sat on the shelf that this created.
I typically carry 22-27 pounds – and need to lcarry all the weight on my hips due to a bad lower back disc.
I don't carry more than 35 because my hip and leg joints can't take it – no matter which pack I use :)
But as long as I pack the weighty items close to my spine, and use the compression straps to keep the pack as flat to my back as possible, and rigid enough to lean against a tree without sagging (noticeably) — then I don't think a frame makes much difference.
Even an inflatable pad works fine as a virtual frame. Fold it so there are 3 layers along your back and it's 1/8 of the way inflated. It will be rigid when you cinch the pack's compression straps tight.
Ps. Foam pads suck on shelter floors. Many people carry a 48" CCF pad for breaks and dinner on wet ground, and cold nights – AND a 2.5" inflatable for sleeping in shelters. Some even carry a full length foam pad instead of a 48" one. Mid day naps are much easier that way :)
Pps: After you walk 500 miles, youll be in much better shape and an extra 2-3 pounds for a frame, better hipbelt, and 10-15 more liters of storage space won't be anything you'll notice. So get enough volume to carry LOTS of food. Your appetite will triple or quadruple.