What a lot of folks find, upon hiking continuously in hot chapparal for the first time, is that the shoes they are accustomed to wearing are too small.
Restricting blood flow creates as many problems as friction.
There are a lot of pretty ugly feet on the PCT for the first couple hundred miles.
Most hikers end up sizing up and leaving the laces a bit loose.
Using two thin socks (think mens dress socks) seems to be better than a single thick sock.
A trick i used was to take my shoes and socks off at every break.
At night i would bury my bare feet in the cool sand for a while just before bed.
Every chance i got i rinsed my socks (away from the water source) and dried them on my pack, sometimes switching back and forth several times a day.
Injinji Toe socks helped me with my toe blisters but others had the opposite experience with them.
Feet are weirdly personal.
One thing seemed to be true for most; by the time you hit Kennedy meadows your feet will be tough as hell… just in time for the spring melt to soften up and slough off all your hard earned callouses!
Definitely look for shoes that breath to start a NoBo PCT hike from the border.
That was a universal success for most hikers i met.
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Here Shootout is air drying his feet during a rest stop on the PCT.
Another hiker friend, Bob Dole, actually cut open the toe box of her Mizunos to make more room for her toes.
At mile 500 her pinky toes were sticking clean outside her shoes!
She ended up getting Mens shoes since they tend to be wider.
I prefer New Balance as the come in EEEE sizes. The cheap 479's are what i used but basically a mostly open mesh top and sides with a decent heel counter worked well for me.
I used superfeet insoles but other had the opposite experience.
Went through 5 pairs of shoes on the PCT.
The EVA midsole of most trail runners will collapse well before the tread is worn and cause all kinds of wierd pains.
Replacing shoes about every 500 miles seems to work for most but some, like Heaps (New Zealand) wore his shoes until the soles actually fell off!
I saw his wierd "flap print" marks in the trail dust before i caught up to him. It was pretty awesome!
A final tactic i used was to apply some body glide to hot spots as they appeared between my toes. This brought instant relief to friction but attracts dirt so you have to wash your feet more often.