Ive had my talon 44 for a year or so and i've loved it.
the only thing i have to complain about is the padding… its very minimal.
although if you pack it right (with your pad folded in thirds against your back and soft materials in the hip belt (bean/hat/gaiters) you'll be fine. plus the only time i've had discomfort with the pack is when i over pack (40-45lbs) normally I'm very comfortable at 30-35lbs though, so you should do five.
when i first got the pack the straps confused the $h!t out of me. but after a few months i got them down pretty good. Every time i went out i would learn something different about the pack, it was kinda fun, getting re-stoked about it every trip; although some are excessive, (i cut off one of the ice axe holders, it only needs one) so cut of what you don't want.
I'm also impressed with the durability, its been through hell and back (plenty of stains and dirt marks) but no tares or wear spots. since these packs are offered every where i recommend you go in and have it fitted properly before you get it, it would make a world of difference.
best of luck,
gunther