Read not too long ago that the FDA is in the process of changing the OTC label. 4 grams/day is way too much!
If you buy in Costco sizes, keep in mind that acetominoPHEN is a metabolite of PHENacitin, a real drain on Ozzie Medicare many decades later.
Remember acute liver failure is a bit harder to treat than acute kidney failure.
That being said, I think most clinicians would consider Tylenol to have less potential for drug interaction. It is not considered an anti-inflammatory agent though. Must use with caution in people who consume significant quantities of EtOH.

