I have a lot of experience in the Exos 58 and find that it is fine to 40 lb if needed, and I have never seen it collapse. Here is a review I did for BGT
http://www.backpackgeartest.org/reviews/Packs/Internal%20and%20External%20Framed%20Backpacks/Osprey%20Exos%2058%20Backpack/Owner%20Review%20by%20Ray%20Estrella/
Will did a BPL review of it too.
I bought the 34 soon after getting the 58 and have a lot of use with it too. All under 25 lb though. I just got a 46 and started using it three weeks ago in preparation of a big hike at the end of the month. I took it on a 3-day water caching trip last weekend. On two days I had three gallons of water inside plus my over-night gear (but no stove/pot) and water for the day/night. The pack handled it better than I did…
I was a huge fan of the Talon series but the Exos has made me switch every size now. The way they keep my back cooler is a big deal. Dave (BIL) and I did a 4-day trip 6 weeks ago that I used the Exos 34 and he used the Talon 22. (Yes he is UL, I am trying.) He was soaked at our rest stops while I was just damp, and normally I am the world’s biggest sweaty Eddie.
Make sure you try it on first! There is no adjustment on this suspension so picking the right size matters. I am 6’ 3” and the Large fits me with room to spare on the shoulders, and the waist belt is almost pulled to the middle. Dave can’t borrow any of mine even though he is 6’ 2” because he has a shorter torso and is skinny (darn him).