Yes, lighter colored, thinner, more breathable, and loose helps no matter what the fabric is.
I prefer blends between synthetic and natural the most, thought straight nylon KNIT fabrics that wick are pretty good too. For the natural fiber, i prefer it to be linen because it doesn't stick as much as cotton, feels drier more quickly, is stronger, and a bit better odor prevention. Tencel is a decent alternative to linen.
But even (all) linen isn't ideal in very humid and hot weather, some synthetic helps. I have a 65% polyester and 35% linen very breathable, thin dress shirt–works great in humid, hot weather. It would be even better if the synthetic was nylon and also wicking (the polyester they used in this shirt isn't the wicking kind, but the shirt still wicks because of the linen).
If stink is not a factor for you, OR Echo shirts are pretty good. They have polygiene treatment, which is pretty durable for anti odor treatment, but will eventually wear off if you keep clothes for a long time. I don't think there is a truly permanent anti odor treatment for synthetics. However, both Merino and linen excel in that area.
Copy and paste from an older thread on the subject:
"The best that i've found are these in order: Synthetic-linen or synthetic-hemp blends, nylon-tencel blend, and Under Armour KNIT nylon "Iso-chill" shirts (very breathable, very wicking, pretty quick drying, and actually feels cool).
Unfortunately, the first two options tend to be pretty hard to find, and the last is fairly expensive (i bought my shirt on clearance)."
I should add that dri release stuff is decent (the ones with a little cotton), but i wish they wicked a bit better. Really good wicking fabric will immediately absorb and really spread out moisture put on the surface. My dri release stuff doesn't absorb as fast, or spread the moisture as much, as some of my good all synthetic wicking stuff or synthetic/natural blends that have a higher percentage of natural fiber.
They are coming out with more and more supposedly "actively cooling" fabrics, but i haven't tried too many because they tend to be rather expensive, and i live in a high humidity area, which reduces effectiveness of a lot of those type of shirts. The Under Amour Iso chill knit nylon shirt is supposed to be in that kind of category. I do like it a lot.