I use down and have never had a problem.
I have one bag and three quilts, but in reality two of the quilts overlap a bit.
I have a Mountain Hadwear Phantom 0 that is 44oz ekk!! It only see's use a few nights in the winter when I go out below the upper teens. I have used this down to 0*. (if it is colder than that, I don't want to be out in it)
I have a Javan Dempsey quilt that has 12oz of down in it that I use from the upper teens to about freezing. It weighs 20.25oz I think an alternitive today would be a 20* quilt from Katabatic, Nunatak, Enlighted Equipment or others.
I also have a Golite Ultra 20 that I use from about freezing to around 50*. I have used this quilt as low as 24* however. I really don't need this quilt with the Javan Dempsey quilt, but this was my first quilt and I can't seem to part with it. It is 18.95oz
Lastly, I have a summer quilt, a BPL Pro 90 Quilt made out of 90 g/m Polarguard Delta that is around 13oz. I use this for temps 50* or above. A replacement today might be the lightest synthetic quilts from EE and MLD. I chose synthetic here because it was the lightest thing I could find and that in a quilt this thin, even down distribution could be a problem.