Gonna take this in stages.
Free Gear Changes:
Leave these items behind:
1 x Wool Socks (I'm assuming that you wore one pair and carried two; you only need to carry one extra pair, if even that much.)
Polyester T-Shirt (Sleep in your wool shirt, instead.)
Kuhl Pants (Bring one set of pants. If you need long johns to sleep in, bring those; they'll be more weight efficient for the warmth than loose hiking pants.)
2 Ziplocks (What were these for? If you're doing FBC, keep these, but otherwise ditch.)
2 Trash Bags (No need for trash bags; use your used FBC bags or carry a single small bag if not doing FBC.)
Pencil
Fishing Hook/Line
Chem Lights
SteriPen (Use the AquaMira instead.)
Spare Headlamp Batteries (Make sure you change the batteries on the headlamp before leaving home for your next trip; this will ensure that you have fresh, charged batteries for the whole trip.)
Travel Size Toothpaste (If you're not on-trail for months at a clip, you'll get most of the benefit of tooth brushing just by brushing without toothpaste.)
Hand Towel (Use your bandanna instead.)
Foil Blanket
Budweiser
Paperback (Load e-books into your iPhone if you really want to read; you won't notice the weight of the extra electrons.)
Minimal Cost Gear Changes:
Change out the pack cover and Sea2Summit dry bags for a 3-mil contractor or lawn trash bag as a pack liner. This will cost ~$5.
Swap out your (heavy!) Primus stove and Isopro for a lightweight alcohol or Esbit stove (many options available for under $20; if you're handy, it'll cost you a pair of aluminum cans and some hardware cloth). Research is worth doing here, but Zelph, Minibull Designs, and Trail Designs are well thought of by most.
Look at your meal list. Make choices that are going to net you your caloric needs per day that are edible, but don't carry anything that's less than ~100 cal/oz on average (the "coffee" is going to pull that average down, but I'm not willing to leave it behind…make your own call here…). Cost is dependent upon what you want to eat, but–often–high calorie meals are cheaper than low calorie meals due to the average American consumer choices. If you choose meals that can be eaten with only a spoon, swap out your "weird plastic spoon/knife/fork thing" for a McFlurry spoon from McDonald's; long handle and lightweight.
Swap out your Camelbak for a pair of 1 L plastic bottles from your local gas station. Smartwater, Gatorade, and Powerade bottles are well-thought of by most (personally, I like the 0.75 L Gatorade bottles with the sport caps, but that's just me). In the Carolina mountains, you'll rarely need more than 1 L of water; carry a second one if it makes you feel better. You almost certainly won't need 3 L of capacity there. If you go elsewhere, revisit this depending on reliable water sources.
Swap out your paracord for 50 ft. of Zing-It or Lash-It from Dutchware ($11, 1.24 oz).
Moderate Cost Gear Changes:
Swap out your ENO Doublenest with straps and 'biners (28 oz + 'biners) for a Dutchware 11' PolyD hammock with whoopie hooks and 5-ft straps ($74, 14.03 oz). Add a structural ridgeline for comfort and ease of set-up ($6.50, 0.32 oz). This nets you a minimum savings of 13.65 oz.
Swap your heavy 22 oz rain fly for a Warbonnet Edge tarp ($85, 11.25 oz before stakes and lines). Add a Dutchware continuous ridgeline for ease of set up ($28, 0.67 oz) and four 6' Zing-It tie outs from Dutchware ($5.50, 0.62 oz). This nets you a minimum savings of 9.46 oz.
Swap the Mammut Kento jacket (12.9 oz) for a Luke's Ultralight silnylon rain shell ($79, 4.2 oz). This nets you a minimum savings of 8.7 oz.
Expensive Cost Gear Changes:
Swap out your REI Radiant +17 for a ZPacks 20* top quilt ($390, 16.7 oz). This nets you a minimum savings of 26.3 oz.
Add a 3-Season Yeti (20* rating, $190, 12.5 oz). This will cost you 12.5 oz, but it will also make sleeping in an hammock much more comfortable than trying to stay on a pad.
Last Gear Change:
Only once you've got everything else figured out on weight and bulk should you change your pack. Assuming that you manage to whittle everything down to the ~10 lb base weight and ~45 L total volume range (completely doable), you can save around 24 to 32 oz on the pack, depending on whether or not you want a frame. Here, pick a pack that fits over any other criteria: an ill-fitting pack is the second-worst thing you can carry on trail (badly fitting shoes are first). Try on as many packs as you can when you make this choice, as it will help you out immensely in making your choice.
The way to know how to fit your pack to your gear weight: add up your base pack weight (this is everything but fuel, food, and water), add 2 lbs/person/day of food weight and 2.2 lbs/liter of water. Do this for the longest (and driest) trip you're going to be out between resupply points. That's the weight your pack needs to be able to carry.
How to fit it to gear volume: take everything (including fuel and water containers), place it in a large cardboard box (or other rectangular container), level it out, and take measurements in both inches and cm. Multiply to find volume (divide your cubic cm result by 1,000 to find liters), and add 2 L/122 cubic in per person/day of food (also, if using collapsible water containers, don't forget to add the amount of L you'll be carrying in water). This is the volume your pack needs to be able to carry.
Hope it helps!