Colorado trip suggestion’s?

Where would you go for a trip in early August that is within two hours drive of Frisco, Colorado, if your wish list included:

* 3-4 days of moderately-paced hiking and climbing with decent portion above treeline. Possibly including hike-able 14er's. Emphasis on tundra/peaks/views/wildflowers.

* Good fly fishing at some point.

* far enough from normally crowded areas as to feel somewhat isolated/alone. We'll be going during the week to help reduce crowds.

I've done a number of hikes in Summit County and also a few 14er's. This will be my first time trying to include fly fishing in a trip like this.

Thanks!