based upon what i’ve read (not from 1st hand experience – never used compression stuff sacks) there are two issues here: one short term, and one long term.
short term:
return to full (near full?) loft, or time to return to full loft
long term:
breakdown of the insulation due to friction and stress (i believe these were the reasons) from the compression.
have read that it effects both down & synth. insulation.